Louisville Lectures Internal Medicine Lecture Series Podcast

Kristen takes a look at adverse drug reactions occurring secondary to identifiable genetic risk factors. She looks at the evidence supporting genetic testing, common mutations (Cyp phenotypes), and how to decide whom to test.

Dr. Sathya Krishnasamy presents cases to illuminate the physiology of thyroid disease including hypothyroidism, hyperthyroidism and thyroid nodules.

Dr. Lorrel Brown covers the common (and less common) results of MI  using cases. She includes papillary muscle rupture and mitral regurgitation, free wall rupture, ventricular septal defects, right ventricular infarct, pseudoaneurysm, aneurysm, pericarditis and bradyarrhythmias. Dr. Brown is an Assistant Professor at the University of Louisville and is the Associate Director of the Cardiovascular Medicine fellowship. Her medical training was completed at Johns Hopkins University. Although a new faculty member, she recently won the Clinical Faculty Teaching Award from the residents. Her areas of interest in cardiac critical care, post-graduate medical education, and in-hospital cardiac arrest. Some items in this lecture may have come from the lecturer’s personal academic files or have been cited in-line or at the end of the lecture. For more information, see our citation page. (https://laura-bishop.squarespace.com/citations) Disclaimers (https://laura-bishop.squarespace.com/disclaimer)©2015 LouisvilleLectures.org

Dr. Gerald Lee discusses common primary immunodeficiencies using a case-based approach. He introduces the topic of immunodeficiencies by creating broad categories of clinical presentation to assist with pattern recognition. He spends more time on Selective IgA Deficiency and then covers Common Variable Immunodeficiency in depth.

Dr, Rodrigo Cavallazzi gives a comprehensive review of ARDS; he includes the definition, pathophysiology, risk factors, prognosis and differential. He spends time discussing the ARDS Network trial including fluid and  ventilation strategies as well as advanced treatments (prone positioning, ECMO, neurally adjusted ventilation. Some items in this lecture may have come from the lecturer’s personal academic files or have been cited in-line or at the end of the lecture. For more information, see our citation page. ©2015 LouisvilleLectures.org

Dr. Charles Moore demystifies ANA testing and medications used for rheumatologic disorders including common side effects and screening for adverse effects. Some items in this lecture may have come from the lecturer’s personal academic files or have been cited in-line or at the end of the lecture. For more information, see our citation page. Disclaimers ©2015 LouisvilleLectures.org

Dr. Lorrel Brown covers the basics of shock including how to recognize cardiac shock from history, physical exam and invasive monitoring. She discusses physiology and interpretation of pulmonary artery catheterization and then covers choice of vasopressors for therapy. Dr. Brown is an Assistant Professor at the University of Louisville and is the Associate Director of the Cardiovascular Medicine fellowship. Her medical training was completed at Johns Hopkins University. Her areas of interest in cardiac critical care, post-graduate medical education, and in-hospital cardiac arrest. Some items in this lecture may have come from the lecturer’s personal academic files or have been cited in-line or at the end of the lecture. For more information, see our citation page. ©2015 LouisvilleLectures.org

For internists not inclined towards cardiology or critical care, an ultrasound might be merely a diagnostic test to be ordered. Research and expertise in this field are expanding rapidly, however, and an affordable handheld ultrasound that can easily be carried in a white coat is likely not many years away. In this lecture, Dr. Nunley discusses the basic principles, physics, and ideas behind ultrasound to give a baseline for moving forward with additional training.   Dr. Nunley is a Professor of Medicine on faculty at the University of Louisville. He is the Clinical Director of the Lung Transplant Program at Louisville and is a teaching attending in the MICU. He has received multiple awards from national organizations including UNOS, American College of Chest Physicians and American College of Critical Care Medicine. His faculty profile can be found here (http://louisville.edu/medicine/departments/medicine/doctors/nunley).

Dr. Charles Moore covers more rheumatology topics including treatment of gout, psoriatic arthritis, and the clinical presentation of Sjögren's syndrome and sicca syndrome. Dr. Moore is an assistant professor of Medicine at University of Louisville in the department of Rheumatology. He trained in Internal Medicine and Pediatrics at University of Louisville then completed a fellowship in Rheumatology at Vanderbilt University. He staffs the adolescent transition clinic for pediatric rheumatology, the lupus clinic, and the faculty practice clinic. Dr Moore's clinical research interests in health services include early detection in both RA and SLE and interventions aimed at enhanced follow-up rates in both these illness and in adolescents.

Dr. Andrew Defilippis discusses his very practical research into the data behind cardiovascular risk scores. His findings on variations between different cohort studies have been published and debated the Annals of Internal Medicine (http://www.ncbi.nlm.nih.gov/pubmed/25686167) this spring. As a set of tools we use daily in our outpatient primary care practice, a deeper dive into cardiovascular risk calculations fits our criteria for being both a Grand Rounds and Louisville Lectures talk. Dr. Andrew Defilippis is an Assistant Professor on faculty the University of Louisville's division of Cardiology. In addition to this, he is a researcher and is the clinical director for the University of Louisville's Cardiac ICU.

Dr. Tanya Wiese gives an overview of lung cancer screening then discusses solitary pulmonary nodules in detail; she covers their definition and workup in addition to the use of endobronchial ultrasound and navigational biopsy in diagnosis. Dr. Wiese is an Assistant Professor with the University of Louisville and is the Director of the Interventional Pulmonology program. In this lecture, Dr. Wiese describes an approach to solitary pulmonary nodules. Her faculty profile can be found here:http://louisville.edu/medicine/depart... (http://louisville.edu/medicine/departments/medicine/doctors/wiese) Disclaimer: http://LouisvilleLectures.org/disclaimer (http://louisvillelectures.org/disclaimer)©2015 LouisvilleLectures.org

Dr. George Bosse gives a thorough review of acetaminophen and salicylic acid pharmacokinetics followed by presenting symptoms, pathology and treatments for toxicity. Disclaimer: http://LouisvilleLectures.org/disclaimer ©2015 LouisvilleLectures.org

In this first of a two part series, Dr. Charles Moore discusses ankylosing spondylitis, polymyositis/dermatomyositis, inclusion body myositis, anti-synthetase syndrome and scleroderma including epidemiology, clinical manifestations, diagnostic criteria and treatments.    

Dr. Lorrel Brown recaps the electrical system of the heart then uses cases to discuss AV blocks, and interprets many EKGs!  Here is your chance to get inside the brain of a cardiologist!

Answering your burning questions about UTIs