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Who'd have thought that a diabetes drug pulled from the shelves because of harmful side effects would shrink lung-cancer tumors? Scientists at Salk Institute's new Helmsley Center for Genomic Medicine had that very idea, and it's panning out.

Last-minute legislation in Washington D.C. delayed the start of the 2013 tax season. The IRS begins accepting tax filings on Wednesday.

The newest generation of implantable heart pumps are keeping many patients alive while they wait for a heart transplant.

A collection of science fiction books, letters and manuscripts, valued at more than $2 million, is now in the hands of the San Diego State University library.

When filmmaker Charlie Minn began documenting the war between rival drug cartels in Juarez, Mexico, the city was on its way to becoming the murder capital of the world. His latest documentary, the New Juarez, tells a different story.

Hundreds of volunteers fanned out across San Diego County to survey the homeless population last Friday, but a lot of work still needs to be done to complete the annual survey.

Mayor Bob Filner outlines push for getting jobs for San Diego veterans.

As talk of immigration reform heats up, farmers want to streamline the guest worker program, while advocates generally oppose it.

A key question hovering over the Convention Center expansion is what role climate change will play.

Alpine Union Elementary School district will start its first bilingual program next fall.

This week marks a milestone in the decades-long debate over whether to develop a new landfill in San Diego’s North County. The Army Corps of Engineers will hear public comment on its draft EIR for Gregory Canyon, one of very few new landfills in the pipeline for a permit in California.

The list of potential candidates for San Diego’s District 4 special election is getting smaller.

A Supreme Court Justice promoted her memoir and spoke to a sell-out crowd at the University of San Diego.

A little bitty beetle is making a meal of San Diego's oak trees -- and could kill them all. The race for City Council District 4 is wide open. Immigration reform may really be coming. And a proposed development is stirring up Carmel Valley folks.

Preventing employers from hiring undocumented immigrants is likely to be a key part of the upcoming debate over immigration reform. We look at what's happening on the ground in Arizona, after the state tried to require strict hiring practices five years ago.