A Conversation with the Author of Reversible Regulation of Aptamer Activity with Effector-Responsive Hairpin Oligonucleotides
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Summary: Aptamers are oligonucleotides that can bind to various nonnucleic acid molecular targets in a high affinity and specificity. As an emerging class of therapeutic agents, aptamers offer an unparalleled advantage over other classes of therapeutic agents: the possibility to rationally regulate the therapeutic activity of aptamers.