![Annals of Internal Medicine Podcast show](https://d3dthqtvwic6y7.cloudfront.net/podcast-covers/000/030/855/small/annals-of-internal-medicine-podcast.jpg)
Summary: Predicting BRCA1 and BRCA2 mutations; clinical practice guidelines for low back pain; and an interview with Dr. Giovanni Parmigiani of Johns Hopkins University and Dr. David Euhus of University of Texas-Southwestern about the use of genetic risk prediction for breast cancer gene mutations in clinical practice.