A Conversation with the Authors of A Serial Sample Loading System: Interfacing Multiwell Plates with Microfluidic Devices

Summary: A novel technique enables serial delivery of sample arrays to a microfluidic device from multi-well plates through a single sample inlet. A serial array of sample plugs, separated by an immiscible carrier fluid, is loaded into a capillary and delivered to a microfluidic device.  The application of a positive pressure based Serial Sample Loading (SSL) system to load the series of sample plugs into the capillary is demonstrated along with the adaptability of the SSL system to generate sample plugs with a variety of volumes in a predictable manner.