Summary: Featuring articles on once-weekly semaglutide in adults with overweight or obesity, neutralizing antibodies to prevent HIV-1 infection, passive immunotherapy in patients with Covid-19, inhibition of C3 in paroxysmal nocturnal hemoglobinuria, and the political nature of sex; a review article on extrahepatic manifestations of chronic HCV infection; a case report of a woman with cholangiocarcinoma; and Perspective articles on private equity and physician medical practices, on the good doctor, and on the intern. Supplement to the New England Journal of Medicine, Vol. 384, No. 11.
