Summary: Featuring articles on ticagrelor and aspirin after a stroke or transient ischemic attack, an RNA early warning for rheumatoid arthritis flares, roflumilast cream for chronic psoriasis, timing of renal-replacement therapy in acute kidney injury, bilateral tumors, diagnosing and treating systemic racism, and structural solutions for the rarest of the rare; a review article on acute ischemic stroke; a case report of a woman with early breast cancer during the Covid-19 pandemic; and Perspective articles on stolen breaths, on creating real change at academic medical centers, on racial health disparities and Covid-19, and on uncertain trust. Supplement to the New England Journal of Medicine, Vol. 383, No. 3.
