Peds S- Sepsis and Serious Bacterial Infections




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Summary: <br> Pediatric “Sepsis”<br> <br> <br> <br> * Consider in any toxic appearing child/neonate* Especially with fever (or hypothermia)* Treatment* Early antibiotics* Fluid bolus<br> <br> <br> <br> “Serious Bacterial Infections” (SBI)<br> <br> <br> <br> * Consider in any baby with fever* Three classic categories* Age &lt;30 days* Introduction* Weak immune system* No immunizations* Very high risk for serious bacterial infections* Require a significant amount of testing* Urinalysis with Urine Culture* Blood Cultures* Lumbar Puncture with CSF Cultures* Chest X-Ray* Require admission and antibiotics* Age 30-60 days* ILL appearing* Treat same as fever in &lt;30 day patient* WELL appearing* Testing and treatment differ by institution* Multiple criteria established to help in this age range* Rochester criteria* Philadelphia criteria* PECARN criteria* Choose one and use consistently* Age &gt;60 days* (Assumes immunizations are up to date)* Workup is more targeted* Blood cultures, Urine cultures, Chest X-Rays still common<br> <br> <br> <br> Additional Reading<br> <br> <br> <br> * Rochester Criteria Febrile Infants <a href="https://www.mdcalc.com/rochester-criteria-febrile-infants">(MDCalc)</a>* PECARN Rule for Low Risk Febrile Infants <a href="https://www.mdcalc.com/pecarn-rule-low-risk-febrile-infants-29-60-days-old">(MDCalc)</a><br>