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Summary: Here's everything you need to know before Wednesday's opening bell: Celgene is reportedly in talks to buy Juno . Ford fell premarket after saying it expects lower operating profit in 2018. Nissan's Infiniti said it will begin phasing our gas-powered vehicles in 2021. Bitcoin prices extended their decline, dropping more than $1000. U.S. stock futures suggested a rebound from yesterday's small loss. Watch More with TheStreet: The Dollar Will Be Replaced By Gold And Cryptos By 2040 - Robert Kiyosaki Wendy's CEO: Here Is What Our Future Looks Like Lamborghini CEO Reveals the Future of the Supercar Watch: Meet This New ETF Tracking Blockchain Related Companies Like IBM