What does a shortened PT/PTT mean in dogs? Hypercoagulability in dogs with Dr. Jennifer Song | VETgirl Veterinary Continuing Education Podcasts

Summary: In today's VETgirl online veterinary continuing education podcast, we interview Dr. Jennifer Song, who recently finished her surgical residency at the Ohio State University Veterinary Medical Center. Dr. Song, a board-eligible veterinary surgeon, discusses a retrospective study that she performed while at PennVet entitled "Retrospective evaluation of shortened prothrombin time or activated partial thromboplastin time for the diagnosis of hypercoagulability in dogs: 25 cases (2006-2011)" in the Journal of Veterinary Emergency Critical Care. Previously, we didn't pay much heed to a shortened PT/PTT; we generally only looked at prolongation as an indicator of hypocoagulability (the inability to clot). However, in recent human studies, there may be some evidence that a shortened PT/PTT is suggestive of hypercoagulability! While thromboelastography (TEG) is traditionally looked at - along with increased fibrin (or fibrinogen) and D-dimers - to evaluate hypercoagulability, Song et al's new evidence may prove otherwise. So, start paying attention to your shorter PT/PTT readings after all!