Summary: Featuring articles on acute kidney injury in critically ill children, disease phenotypes and multilocus genomic variation, ticagrelor vs. clopidogrel in peripheral artery disease, RNAi inhibitor of PCSK9, and delivering on oligonucleotide therapeutics; review articles on the large pharmaceutical company perspective and on arrhythmogenic right ventricular cardiomyopathy; a Clinical Problem-Solving article describing after the party's over; and Perspective articles on the end of Obamacare, on oligonucleotide therapeutics, and on a view from the edge.
