TED: Uri Alon: Why truly innovative science demands a leap into the unknown - Uri Alon (2013)

Summary: While studying for his PhD in physics, Uri Alon thought he was a failure because all his research paths led to dead ends. But, with the help of improv theater, he came to realize that there could be joy in getting lost. A call for scientists to stop thinking of research as a direct line from question to answer, but as something more creative. It's a message that will resonate, no matter what your field.