This Week in Evolution show

This Week in Evolution

Summary: This Week in Evolution is a podcast on the biology of what makes us tick. Hosts Nels Elde and Vincent Racaniello take you through the new evolution that has been revolutionized by the field of genomics and molecular biology.

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  • Artist: Vincent Racaniello
  • Copyright: Copyright 2020 Vincent Racaniello

Podcasts:

 TWiEVO 56: Revising the drafts of coronavirus evolution | File Type: audio/mpeg | Duration: 01:28:05

Nels and Vincent continue their discussion of SARS-CoV-2 evolution, including understanding recurrent mutations in the viral genome, and the potential for re-emergence of the virus from an animal reservoir.

 TWiEVO 55: Coronavirus evolution from soup to nuts | File Type: audio/mpeg | Duration: 01:13:51

Nels and Vincent continue their discussion of SARS-CoV-2 evolution, with a report that the coronavirus proofreading enzyme stimulates RNA recombination, and debunking the conclusion that a change in the viral spike glycoprotein is associated with increased human to human transmission.

 TWiEVO 54: Rough drafts of SARS-CoV-2 science | File Type: audio/mpeg | Duration: 01:17:41

Nels and Vincent continue their discussion of SARS-CoV-2 from an evolutionary viewpoint, including function of the furin cleavage site, whether Vervet cells are an informative system, another bat isolate, and a nomenclature to assist genomic epidemiology.

 TWiEVO 53: Virus evolution by land and by sea and by CoV, part II | File Type: audio/mpeg | Duration: 01:31:53

Nels and Vincent continue their discussion of SARS-CoV-2 from an evolutionary viewpoint, focusing on what the genome sequences tell us about the virus.

 TWiEVO 52: Virus evolution by land and by sea and by CoV | File Type: audio/mpeg | Duration: 01:22:43

Nels and Vincent examine SARS-CoV-2 from an evolutionary viewpoint, examining what the spike glycoprotein sequence informs us about the origin of the virus.

 TWiEVO 51: The starting point paradox | File Type: audio/mpeg | Duration: 01:10:51

Nels and Vincent dive deep into evolution and consider how new proteins emerged billions of years ago, when there were no other proteins to serve as starting material.

 TWiEVO 50: I'm dreaming of a Y chromosome | File Type: audio/mpeg | Duration: 01:42:57

Nels and Vincent discuss signatures of sex chromosome evolution revealed by assembly of a young vertebrate Y chromosome from 3-spined stickleback fish.

 TWiEVO 49: A giant podcast on giant viruses | File Type: audio/mpeg | Duration: 01:53:11

Rich joins Nels and Vincent for a debriefing on the 4th Ringberg Symposium on Giant Virus Biology in Tegernsee, Germany.

 TWiEVO 48: Flipping out with choanos on caffeine | File Type: audio/mpeg | Duration: 01:34:29

Nels and Vincent reveal a new choanoflagellate that forms multicellular cup shaped colonies that respond to light to alternate between feeding and swimming behavior.

 TWiEVO 47: On the origin of beer species | File Type: audio/mpeg | Duration: 01:31:43

Nels and Vincent trace the origins of Saccharomyces cerevisiae strains used to make beer, and find that ales and lagers are made with yeasts that were derived from those used to make European grape wine and Asian rice wine.

 TWiEVO 46: Can an old tumor teach us new tricks? | File Type: audio/mpeg | Duration: 01:32:05

Nels and Vincent analyze the genomes of canine transmissible tumors to provide insight into the worldwide spread of the disease from its origin in a single dog 4000-8500 years ago, and its diversity, mutation, and evolution.

 TWiEVO 45: Microbial secrets of mouse-ear cress | File Type: audio/mpeg | Duration: 01:02:01

At ASM Microbe in San Francisco, Nels and Vincent meet up with Talia Karasov who reveals that in contrast to agriculture, wild plants are colonized by multiple lineages of pathogenic bacteria.

 TWiEVO 44: The enemy of my enemy is my phage | File Type: audio/mpeg | Duration: 01:04:31

At ASM Microbe in San Francisco, Nels and Vincent meet up with Paul Turner to talk about evolutionary considerations in using bacteriophages to treat infections with antibiotic-resistant bacteria.

 TWiEVO 43: Social evolution with a side of shrimp | File Type: audio/mpeg | Duration: 01:20:37

Dustin Rubinstein joins Nels and Vincent to discuss coevolution of genome architecture and social behavior, and studying social transitions in sponge-dwelling snapping shrimp.

 TWiEVO 42: Who's who in your genome | File Type: audio/mpeg | Duration: 01:18:31

Nels and Vincent review the contribution of multiple Denisovan lineages to the modern Papuan genome.

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